Shattuck Labs Inc (NAS:STTK)
$ 7.24 -0.09 (-1.23%) Market Cap: 344.27 Mil Enterprise Value: 236.98 Mil PE Ratio: 0 PB Ratio: 2.67 GF Score: 66/100
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Shattuck Labs Inc at Evercore ISI HealthCONx Conference (Virtual) Transcript

Nov 29, 2022 / 06:00PM GMT
Release Date Price: $2.18 (-0.46%)
Jonathan Miller
Evercore ISI - Analyst

Good afternoon everybody. Welcome to our fireside with Shattuck. Thanks, Taylor, for joining us. We're very excited to get into the nitty-gritty here, but why don't I start by Taylor giving you an opportunity to intro the platform a little bit. Can you tell us a little bit about your ARCs and your approach to immunostimulation?

Taylor Schreiber
Shattuck Labs, Inc. - CEO & Co-founder

Sure. Hi Jon, Hi Eric, thanks for the invitation. So the agonist redirected checkpoint or ARC platform is a two-sided Fc-fusion protein platform where one end of these molecules is aimed at blocking different immune checkpoints and the other end is aimed at activating co-stimulatory receptors in the TNF superfamily.

To do that well, these molecules need to -- any TNF receptor agonist really needs to attain at least a trimeric, but even better if it's a hexameric configuration. That's something that we've learned through over 20 years of Phase 1 trials with monoclonal antibodies going after targets like CD40 that just have not

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