Aeglea Bio Therapeutics Inc at Stifel Immunology and Inflammation Virtual Summit Transcript

Sep 20, 2023 / 03:00PM GMT
Alex Thompson - Stifel, Nicolaus & Company, Inc. - Analyst

Great. Good morning, everyone. We're back again. We have Cameron Turtle, COO of Aeglea BioTherapeutics here with us for a fireside chat. I'm going to turn it over to Cameron now to give a brief overview of Spyre, and then we'll get into the Q&A.

Cameron Turtle - Aeglea BioTherapeutics, Inc. - COO

Sounds good. Thanks, Alex, and thanks, everyone, for taking the time this morning. So our ambition with Spyre is pretty straightforward, which is to develop a next generation of IBD therapies that we think can provide a step change in the convenience and efficacy of therapies compared to what's currently available as standard of care.

And in particular, we're aiming to do this with really three strategic pillars here, which is, first, making extended half-life, high-concentration antibodies against what we think are the best targets in IBD, which are alpha 4, beta 7, TL1A, and IL-23, the first two of which we expect our programs to go into the clinic next year. And common to all of these

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