Fusion Pharmaceuticals Inc at Bloom Burton & Co Healthcare Investor Conference Transcript

Apr 25, 2023 / 07:00PM GMT
John Valliant - Fusion Pharmaceuticals, Inc. - CEO

Thank you, and thank you, everyone, for attending. So I'm very excited to talk to you about the radiopharmaceutical field, which is undergoing a tremendous resurgence. It's a field that I've been in for 30 years. And one of the exciting parts about this idea of targeting radiation to specific cancer cells builds on the success of external beam radiation therapy. And so the idea of being able to use radiation to treat metastatic cancers is an idea that's been around for a number of years. There's some early promising clinical data, but we're seeing a tremendous resurgence in the field.

And so the idea is leverage the very simple mechanism of action associated with how radiation kills cells, but then use targeting molecules to bring radiation inside the tumor cells to cause largely double-strand DNA break and [leafill] kills to the tumor cell. It is a true type of precision medicine because one of the powers of the radiopharmaceutical field is you can see where your drug is going, the ability to image a patient, identify target mediated uptake in

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