- The Facility represents the first semi-automated gene editing trait production system that provides a time-bound, predictable and reproducible breeding system for the editing of commercial plants.
- The Facilityâs Trait MachineTM process edits directly into a customersâ elite germplasm, increasing speed and scale of trait development & commercialization.
- The Facility provides Cibus the gene editing production capacity to support the commercial launch of its first three developed traits across canola, winter oilseed rape, and rice.
SAN DIEGO, July 12, 2023 (GLOBE NEWSWIRE) -- Cibus, Inc. ( CBUS), a leading agricultural technology company that develops and licenses plant traits to seed companies for royalties, announced the opening of its Oberlin facility in San Diego with its first Production Run. The 32,000 square foot Oberlin facility, powered by Cibusâ proprietary Trait Machine⢠process, is the first high-throughput trait production system for plants. The completion of this facility is an important step in Cibusâ vision of the Future of Breeding that integrates High Throughput Gene Editing Systems as extensions of seed company breeding programs. With the Trait Machine process, Cibus is able to fundamentally change the way seed companies bring new traits into their advanced product pipelines and significantly accelerate the pace at which new trait innovation is delivered to the farmers.
âThe Cibus Trait Machine process changes how agricultural trait products are commercialized using proprietary breeding technologies. It allows customers to select their most appropriate elite germplasm to be edited by Cibus. Cibus, in turn, returns to its customers seeds which contain the edits and can be used immediately in the advanced stage of their customerâs breeding program,â said Peter Beetham, President and Chief Operating Officer of Cibus. Beetham added: âThis is the âFuture of Breedingâ and why the Trait Machine and Oberlin facility are so important. We are enabling a new scale and speed for farmers to access new traits that will help them produce higher yields at lower costs, in a more sustainable way to address the challenges of climate change.â
The Trait Machine process employed at the Oberlin facility integrates crop specific RTDSÂŽ cell biology platforms with a series of gene editing technologies to enable a system of end-to-end crop specific precision breeding. Oberlin is currently operational for canola, winter oilseed rape, and rice. The company is dedicated to also establish cell biology platforms for soybean, wheat, and corn within the foreseeable future â the work on soybean is most advanced. Cibus has developed traits for both canola and winter oilseed rape, and in 2023, began transferring back to customers their elite germplasm with Cibus traits. The high-throughput capacity provided by the Oberlin production facility is important to enable Cibus to meet the demand from its seed company customers for its proprietary traits and for the development of future traits.
âThe opening and commissioning of Oberlin, provides Cibus the needed production capacity to support the commercial launch of our developed traits in canola, winter oilseed rape, and rice,â said Andrew Walker, Cibusâ Vice President Production. âWe are already initiating gene editing production runs directly in the elite germplasm of eleven different seed companies who have provided Cibus the materials to edit our traits directly into their elite lines. This type of gene editing production system allows our customers to bypass the conventional trait introgression breeding approach which can be time consuming, labor intensive, and less precise.â
âWith Oberlin now fully operational, we are just scratching the surface on the potential of high-throughput gene-editing. This is the start of a new era. Our expectation is that it will be the model for how gene-editing-as-a-service is accessed by seed companies going forward, with the ultimate goal of providing innovation that delivers benefits directly to the farmers.â added Greg Gocal, Executive Vice President and Chief Scientific Officer of Cibus. âIn addition, as this facility increases the scale and throughput of our gene-editing processes, it also allows us to more rapidly test and prototype new trait concepts, building on the success of our advanced commercial-ready traits.â
About the Trait Machineâ˘
A key element of Cibusâ technology breakthrough is its Trait Machine process. The Trait Machine process is a crop specific application of Cibusâ patented Rapid Trait Development System (RTDS). The proprietary technologies in RTDS integrate crop specific cell biology platforms with a series of gene editing technologies to enable a system of end-to-end crop specific precision breeding. It is the core technology platform for Cibusâ Trait Machineâ˘: the first standardized end-to-end semi-automated crop specific gene editing system that directly edits a seed companyâs elite germplasm. Each Trait Machine process requires a crop specific cell biology platform that enables Cibus to edit a single cell from a customersâ elite germplasm and grow that edited cell into a plant with the Cibus edits. Cibus has Trait Machine processes developed for canola, winter oilseed rape, and rice and has already begun transferring back to customers their elite germplasm with Cibus edits in both canola and rice.
The traits from the Trait Machine process are indistinguishable from traits developed using conventional breeding or from nature. Under the European Commission proposal, products from Cibusâ RTDS gene editing platform such as its pod shatter reduction trait and Sclerotinia resistant traits for canola and winter oilseed rape would be considered âConventional-like'.
Cibus believes that RTDS and the Trait Machine process represent the technological breakthrough in plant breeding that is the ultimate promise of plant gene editing: âHigh Throughput Gene Editing Systems operating as an extension of seed company breeding programs.â The technological moment that materially changes the speed, breadth, and scale of trait development.
About Cibus
Cibus is part of the multi-billion-dollar plant seed industry. Cibus is the leader in the new era of high throughput gene editing technology that can develop plant traits precisely and predictably at a fraction of the time and cost of conventional breeding. Cibus is not a seed company. It is a technology company that develops and licenses traits to seed companies in exchange for royalties on seed sales. Cibusâ target market is Productivity Traits that improve yields, lower input costs such as chemicals, and increases the sustainability and profitability of farming. It has a pipeline of six productivity traits including important traits for pod shatter reduction, disease resistance, and nutrient use efficiency. Cibusâ focus is scale, multi-crop traits that can impact greater than 100 MM acres.
Forward Looking Statements
This press release contains âforward-looking statementsâ within the meaning of applicable securities laws, including The Private Securities Litigation Reform Act of 1995. All statements, other than statements of present or historical fact included herein, including statements regarding the benefits of the merger, Cibusâ operational and financial performance, and Cibusâ strategy, future operations, prospects and plans, are forward-looking statements. Forward-looking statements may be identified by words such as âanticipate,â âbelieve,â âintendâ, âexpect,â âplan,â âscheduled,â âcould,â âwouldâ and âwill,â or the negative of these and similar expressions.
These forward-looking statements are based on the current expectations and assumptions of Cibusâ management about future events, which are based on currently available information. These forward-looking statements are subject to numerous risks and uncertainties, many of which are difficult to predict and beyond the control of Cibus.
There are many factors that could cause Cibusâ actual results, level of activity, performance or achievements to differ materially from those expressed or implied by forward-looking statements, including factors related to: (i) risks associated with the possible failure to realize certain anticipated benefits of the transactions contemplated by the merger (the âTransactionsâ), including with respect to future financial and operating results; (ii) the effect of the completion of the Transactions on Cibusâ business relationships, operating results and business generally; (iii) the outcome of any litigation related to the merger agreement or Transactions; (iv) competitive responses to the Transactions and changes in expected or existing competition; (v) challenges to Cibusâ intellectual property protection and unexpected costs associated with defending Cibusâ intellectual property rights; (vi) increased or unanticipated time and resources required for Cibusâ platform or trait product development efforts; (vii) Cibusâ reliance on third parties in connection with its development activities; (viii) Cibusâ ability to effectively license its productivity traits and sustainable ingredient products; (ix) the recognition of value in Cibusâ products by farmers, and the ability of farmers and processors to work effectively with crops containing Cibusâ traits; (x) Cibusâ ability to produce high-quality plants and seeds cost effectively on a large scale; (xi) Cibusâ need for additional funding to finance its activities and challenges in obtaining additional capital on acceptable terms, or at all; (xii) Cibusâ dependence on distributions from Cibus Global to pay taxes and cover Cibusâ corporate and overhead expenses; (xiii) regulatory developments that disfavor or impose significant burdens on gene-editing processes or products; (xiv) Cibusâ ability to achieve commercial success; (xv) commodity prices and other market risks facing the agricultural sector; and (xvi) technological developments that could render Cibusâ technologies obsolete .
In addition to these factors, other known and unknown risks and uncertainties may adversely affect such forward-looking statements and cause Cibusâ actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements. Should one or more of these risks or uncertainties occur, or should underlying assumptions prove incorrect, actual results and plans could differ materially from those expressed in any forward-looking statements. In addition, the forward-looking statements included in this press release represent Cibusâ views as of the date hereof. Cibus specifically disclaims any obligation to update such forward-looking statements in the future, except as required under applicable law. These forward-looking statements should not be relied upon as representing Cibusâ views as of any date subsequent to the date hereof.
CIBUS CONTACTS:
INVESTOR RELATIONS
Karen Troeber
[email protected]
858-450-2636
MEDIA RELATIONS
Ted Lowen
[email protected]
914-343-6794
Colin Sanford
[email protected]
203-918-4347