Centessa Pharmaceuticals Announces Additional 18-Months of Continued Treatment Data from Open-Label Extension (OLE) of Phase 2a Study of SerpinPC for Hemophilia

Dec 10, 2022

Oral presentation at American Society of Hematology (ASH) Annual Meeting highlights continued favorable safety and tolerability profile and sustained long-term efficacy results for SerpinPC:
- 93% reduction in median ABR for both all-bleeds and spontaneous joint bleeds in highest dose tested
- No thromboembolic events or treatment-related sustained elevations of D-dimer observed
Pivotal program for SerpinPC in hemophilia B advancing; PRESent-5 observation study to begin in the coming weeks

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